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Helena Cirule Selected Research

methyl-gamma-butyrobetaine

8/2017Decrease in Long-Chain Acylcarnitine Tissue Content Determines the Duration of and Correlates with the Cardioprotective Effect of Methyl-GBB.
9/2015Methyl-γ-butyrobetaine decreases levels of acylcarnitines and attenuates the development of atherosclerosis.

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Helena Cirule Research Topics

Disease

5Infarction (Infarctions)
08/2017 - 06/2002
5Ischemia
01/2014 - 06/2002
4Myocardial Infarction
01/2021 - 08/2009
2Reperfusion Injury
01/2021 - 08/2009
2Type 2 Diabetes Mellitus (MODY)
12/2020 - 08/2009
2Hyperlipidemias (Hyperlipidemia)
12/2020 - 05/2011
2Heart Failure
12/2020 - 01/2020
2Hyperglycemia
12/2020 - 05/2011
2Cardiovascular Diseases (Cardiovascular Disease)
01/2020 - 11/2014
2Atherosclerosis
09/2015 - 11/2014
2Hypertension (High Blood Pressure)
01/2014 - 01/2011
2Coronary Occlusion
08/2009 - 06/2002
2Pain (Aches)
08/2009 - 03/2008
2Cardiac Arrhythmias (Arrythmia)
08/2009 - 06/2002
1Liver Failure
04/2024
1Sepsis (Septicemia)
04/2024
1Pulmonary Hypertension
12/2021
1Inflammation (Inflammations)
12/2021
1COVID-19
12/2021
1Ventricular Dysfunction
12/2021
1Left Ventricular Dysfunction
12/2021
1Hypertrophy
12/2021
1Metabolic Syndrome (Dysmetabolic Syndrome X)
01/2021
1Insulin Resistance
01/2021
1Mitochondrial Diseases (Mitochondrial Disease)
12/2020
1Acute Kidney Injury (Acute Renal Failure)
11/2020
1Hydronephrosis
11/2020
1Body Weight (Weight, Body)
01/2020
1Right Ventricular Dysfunction
01/2020
1Atherosclerotic Plaque (Atheroma)
09/2015
1Obesity
05/2011
1Weight Gain
05/2011
1Glucose Intolerance
05/2011
1Cardiomegaly (Heart Hypertrophy)
01/2011
1Diabetes Complications
08/2009
1Necrosis
08/2009

Drug/Important Bio-Agent (IBA)

9Carnitine (L-Carnitine)FDA LinkGeneric
11/2020 - 08/2009
7Fatty Acids (Saturated Fatty Acids)IBA
04/2024 - 08/2009
63-(2,2,2-trimethylhydrazine)propionateIBA
12/2021 - 08/2009
5Glucose (Dextrose)FDA LinkGeneric
04/2024 - 08/2009
3acylcarnitineIBA
01/2021 - 09/2015
2Insulin (Novolin)FDA Link
01/2021 - 01/2014
2trimethyloxamine (trimethylamine N-oxide)IBA
01/2020 - 11/2014
2methyl-gamma-butyrobetaineIBA
08/2017 - 09/2015
22- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA
06/2013 - 06/2012
2SaltsIBA
01/2011 - 08/2009
1Blood Proteins (Serum Proteins)IBA
04/2024
1Pyruvic Acid (Pyruvate)IBA
01/2021
1empagliflozinIBA
12/2020
1Sodium-Glucose Transporter 2 InhibitorsIBA
12/2020
1LipidsIBA
12/2020
1Sodium-Glucose Transport ProteinsIBA
12/2020
1Furosemide (Lasix)FDA LinkGeneric
11/2020
1MonocrotalineIBA
01/2020
1Brain Natriuretic Peptide (Natrecor)FDA Link
01/2020
1Proteins (Proteins, Gene)FDA Link
01/2020
1EstersIBA
09/2015
1gamma-butyrobetaine (butyrobetaine)IBA
09/2015
1Apolipoproteins E (ApoE)IBA
09/2015
1gamma-Butyrobetaine DioxygenaseIBA
07/2014
1magnesium nitrateIBA
01/2014
1MagnesiumIBA
01/2014
1Lactic Acid (Lactate)FDA LinkGeneric
01/2014
1NitritesIBA
01/2014
1NitratesIBA
01/2014
1Carnitine O-Palmitoyltransferase (Carnitine Palmitoyltransferase II)IBA
06/2013
1Cytochromes c (Cytochrome c)IBA
06/2012
1Metformin (Glucophage)FDA LinkGeneric
05/2011
1Peroxisome Proliferator-Activated Receptors (PPAR)IBA
05/2011
1FructosamineIBA
08/2009
1Anti-Arrhythmia AgentsIBA
08/2009
1Phenylephrine (Neo-Synephrine)FDA LinkGeneric
08/2009
1Orotic AcidIBA
08/2009
1Blood Glucose (Blood Sugar)IBA
08/2009
1CarbohydratesIBA
08/2009
1Isoproterenol (Isoprenaline)FDA LinkGeneric
08/2009
1Antidepressive Agents (Antidepressants)IBA
03/2008
14-amino-3-phenylbutyric acid (phenibut)IBA
03/2008
1Guanidine (Guanidine Nitrate)FDA Link
06/2002
11- (3,4- dimethoxy- 2- - chlorobenzylideneamino)guanidineIBA
06/2002

Therapy/Procedure

1Drug Therapy (Chemotherapy)
11/2020
1Mediterranean Diet
01/2020
1Subcutaneous Injections
01/2020